Annual Trends in Ultrasonography-Guided 14-Gauge Core Needle Biopsy for Breast Lesions
- Author:
Inha JUNG
1
;
Kyunghwa HAN
;
Min Jung KIM
;
Hee Jung MOON
;
Jung Hyun YOON
;
Vivian Youngjean PARK
;
Eun Kyung KIM
Author Information
- Publication Type:Original Article
- Keywords: Breast cancer; Ultrasonography; Image-guided biopsy; Trends
- MeSH: Biopsy; Biopsy, Large-Core Needle; Breast Neoplasms; Breast; Carcinoma, Intraductal, Noninfiltrating; Image-Guided Biopsy; Information Systems; Odds Ratio; Retrospective Studies; Ultrasonography
- From:Korean Journal of Radiology 2020;21(3):259-267
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To examine time trends in ultrasonography (US)-guided 14-gauge core needle biopsy (CNB) for breast lesions based on the lesion size, Breast Imaging-Reporting and Data System (BI-RADS) category, and pathologic findings.MATERIALS AND METHODS: We retrospectively reviewed consecutive US-guided 14-gauge CNBs performed from January 2005 to December 2016 at our institution. A total of 22,297 breast lesions were included. The total number of biopsies, tumor size (≤ 10 mm to > 40 mm), BI-RADS category (1 to 5), and pathologic findings (benign, high risk, ductal carcinoma in situ [DCIS], invasive cancer) were examined annually, and the malignancy rate was analyzed based on the BI-RADS category.RESULTS: Both the total number of US scans and US-guided CNBs increased while the proportion of US-guided CNBs to the total number of US scans decreased significantly. The number of biopsies classified based on the tumor size, BI-RADS category, and pathologic findings all increased over time, except for BI-RADS categories 1 or 2 and category 3 (odds ratio [OR] = 0.951 per year, 95% confidence interval [CI]: 0.902, 1.002 and odds ratio = 0.979, 95% CI: 0.970, 0.988, respectively). Both the unadjusted and adjusted total malignancy rates and the DCIS rate increased significantly over time. BI-RADS categories 4a, 4b, and 4c showed a significant increasing trend in the total malignancy rate and DCIS rate.CONCLUSION: The malignancy rate in the results of US-guided 14-gauge CNB for breast lesions increased as the total number of biopsies increased from 2005 to 2016. This trend persisted after adjusting for the BI-RADS category.
