Changes in Interictal Cerebral Blood Flow in Patients with Epilepsy.
- Author:
Kwang Soo KIM
1
;
Ji Hyun LEE
;
Min Jeong KIM
;
Jong Kuk KIM
;
Bong Goo YOO
Author Information
1. Department of Neurology, Kosin University College of Medicine, Busan, Korea. nekim@ns.kosinmed.or.kr
- Publication Type:Original Article
- Keywords:
Cerebral blood flow;
Epilepsy;
Transcranial Doppler sonography (TCD)
- MeSH:
Adult;
Anterior Cerebral Artery;
Basilar Artery;
Blood Flow Velocity;
Carotid Artery, Internal;
Cerebral Arteries;
Electroencephalography;
Epilepsy*;
Hemodynamics;
Humans;
Middle Cerebral Artery;
Posterior Cerebral Artery;
Seizures;
Ultrasonography, Doppler, Transcranial
- From:Journal of Korean Epilepsy Society
2006;10(1):24-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the cerebral hemodynamic changes during interictal period in patients with epilepsy, we investigated changes in cerebral blood flow velocities by transcranial Doppler sonography (TCD). METHODS: Blood flow velocities and pulsatility indecies were measured in both anterior cerebral arteries, middle cerebral arteries, posterior cerebral arteries, internal carotid arteries, and basilar artery using TCD in 21 patients with epilepsy and 21 age and sex matched normal adults. We also evaluated the effects of seizure type, seizure frequency, EEG findings, and anticonvulsant medication on cerebral blood flow velocities. RESULTS: The blood flow velocities of cerebral arteries were decreased in patients, but the pulsatility indecies weren't different. Cerebral blood flow velocities were influenced by seizure type, EEG findings, or anticonvulsant medication. CONCLUSION: Our study demonstrates that cerebral blood flow velocities might be decreased during interictal period in patients with epilepsy, and suggests that TCD is an useful method for the investigation of the cerebral hemodynamic changes in epilepsy.
