Evaluation of CT angiography vascular localization combined with refined three-dimensional printing in guiding the resection and reconstruction of complex oral cancer
10.3760/cma.j.issn.0253-3766.2019.07.003
- VernacularTitle: CT血管造影血管定位联合精细化三维打印指导复杂口腔癌切除与修复的效果
- Author:
Shuichao GAO
1
;
Hao TIAN
1
;
Jianjun YU
1
;
Xing CHEN
1
;
Liang ZUO
1
;
Xu CAI
1
;
Lei SHI
2
;
Bo SONG
3
;
Xiao ZHOU
1
Author Information
1. The Second Department of Head and Neck Surgery, Hunan Cancer Hospital, Changsha 410000, China
2. Department of Hepatobiliary Surgery, Hunan Cancer Hospital, Changsha 410000, China
3. Department of Diagnostic Radiology, Hunan Cancer Hospital, Changsha 410000, China
- Publication Type:Journal Article
- Keywords:
Oral and maxillofacial neoplasms;
CT angiography;
3D printing;
Surgical guide plate;
Reconstruction
- From:
Chinese Journal of Oncology
2019;41(7):496-500
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of vascular localization using computerized tomography angiography (CTA) combined with refined three dimensional (3D) printing in guiding the resection and reconstruction of complex oral cancer.
Methods:From December 2013 to July 2017, the clinical data of 30 patients with complex oral cancer enrolled in the Hunan Cancer Hospital were retrospectively analyzed. 15 patients received CTA+ 3D assisted surgery, while the other 15 patients underwent traditional surgery. In CTA+ 3D assisted surgery group, CT and Magnetic Resonance Imaging (MRI) data were combined with CTA to print refined solid 3D model and surgical guide plate. The preoperative and intraoperative virtual surgical system and the operative experience were combined for preoperative evaluation and surgery. In traditional surgery group, preoperative evaluation and surgery were performed according to imaging data and surgeons′ clinical experience. Operative time, intraoperative blood loss, hospital stay and local recurrence rate were compared between the two groups.
Results:In CTA+ 3D assisted surgery group, one patient gave up surgical treatment after intuitively watching the lesion through the 3D model, and the remaining 14 patients underwent surgery as planned. All the 15 patients in traditional surgery group received surgery. But the preoperative plans of three patients were temporarily and passively modified due to insufficient preoperative evaluation. The average intraoperative blood loss was(320.1±27.2)ml in CTA+ 3D assisted surgery group and(430.2±30.3)ml in traditional surgery group. Mean operation time was(440.3±19.2)min and(552.2±23.3)min, respectively. Mean hospitalization time was (20.4±3.2)d and (25.1±3.7)d, respectively. The differences were all statistically significant (all P<0.05). 1 year and 3 years local recurrence rates were 9.1% and 28.6% in CTA+ 3D assisted surgery group, as well as 14.3% and 50.4% in traditional surgery group with statistical significance (P<0.05).
Conclusion:For complex oral cancer patients with difficulty in opening the mouth or postoperative recurrence, CTA vascular localization combined with fine 3D printing technology has significant advantages in the surgical process, surgical effect and postoperative evaluation index compared with traditional method using imaging data and clinical experience.
