Paying attention to the diagnosis and treatment of IgG4-related sclerosing cholangitis
10.3760/cma.j.issn.0529-5815.2019.07.006
- VernacularTitle: 应重视IgG4相关性胆管炎的诊断和治疗
- Author:
Binglu LI
1
;
Jianchun XIAO
Author Information
1. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
- Publication Type:Journal Article
- Keywords:
Cholangitis;
Diagnosis;
Treatment
- From:
Chinese Journal of Surgery
2019;57(7):508-512
- CountryChina
- Language:Chinese
-
Abstract:
IgG4-related sclerosing cholangitis (IgG4-SC) is characterized by biliary strictures and obstructive jaundice.Elevated levels of serum IgG4 and a multifocal IgG4-rich lymphoplasmacytic infiltration of affected organs are also the characteristics of IgG4-SC. Prednisone is recommended in the initial treatment of IgG4-SC. The differential diagnosis between IgG4-SC and cholangiocarcinoma is not easy. Comprehensively collection of medical history, paying attention to other organs involvement, and getting the pathologic diagnosis are important for diagnosis of this disease. In order to prevent misdiagnosis we should learn more about IgG4-SC. On the other hand, if we can not differentiate IgG4-SC and cholangiocarcinoma, operation may be recommended.
