Advance in epithelial-mesenchymal transition in chronic rhinosinusitis

VernacularTitle: 上皮-间质转化与慢性鼻窦炎的研究进展
Author: Yunbo GAO ¹ ; Yuan ZHANG ^{1
,

2} ; Luo ZHANG ^{1
,

2}
Author Information

1. Deparment of Otolaryngology Head and Neck Surgery and Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
2. Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing 100005, China
Publication Type:Review
Keywords: Sinusitis; Epithelial-mesenchymal transition; Transforming growth factor beta
From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2019;54(3):231-236
CountryChina
Language:Chinese
Abstract: Chronic rhinosinusitis is a common disease in otorhinolaryngology, which has chronic inflammation in mucosa of nasal cavity and sinus. The mechanisms of chronic rhinosinusitis is still unknown. Recently, some studies show that tissue remodeling has important roles in chronic rhinosinusitis, and as a part of tissue remodeling, epithelial-mesenchymal transition also received high attention. Therefore, this review will summarize the present studies involve epithelial-mesenchymal transition and chronic rhinosinusitis, so as to provide reference for further exploring the pathogenesis of chronic sinusitis.