Multi-site analysis of acute effects of air pollutants combination exposure on mortality in Jiangsu Province, China
10.3760/cma.j.issn.0253-9624.2019.01.012
- VernacularTitle: 江苏省大气污染物联合暴露对人群死亡风险急性效应的多中心研究
- Author:
Qingqing WANG
1
;
Yunjie YE
1
;
Jiayao ZHANG
2
;
Hong SUN
1
;
Lian ZHOU
1
;
Zhen DING
1
;
Yan XU
1
Author Information
1. Department of Environment Health, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
2. School of Public Health Nanjing Medical University, Nanjing 211166, China
- Publication Type:Journal Article
- Keywords:
Air pollutants;
Mortality;
Multicenter study;
Time-series
- From:
Chinese Journal of Preventive Medicine
2019;53(1):86-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the acute effect of fine particulate matters (PM2.5), O3, NO2 on daily non-accidental mortality, cardiovascular disease mortality and respiratory mortality data in thirteen cities of Jiangsu province.
Methods:Daily average concentrations of non-accidental mortality, cardiovascular disease mortality, respiratory mortality data and environmental data were collected from January 1, 2015 to December 31, 2017 in thirteen cities of Jiangsu Province. Daily air quality, mortality and meteorology data were collected from the Information System of Air Pollution and Health Impact Monitoring of Chinese Center for Disease Control and Prevention. We used generalized additive model to evaluate the association between daily concentrations of air pollutants and mortality at single-city level and multi-city level, after adjusting the long-term and seasonal trend, as well as meteorological factors and the effect of "days and weeks" . A multivariate Meta-analysis with random effects was applied to estimate dose-response relationship between air pollutants and mortality.
Results:At multi-city level, per interquartile range increase of PM2.5, O3, NO2 was associated with an increase of 1.10% (95%CI: 0.66%, 1.54%), 0.59% (95%CI: 0.18%, 1.00%), 2.00% (95%CI: 1.29%, 2.72%) of daily non-accidental mortality respectively; 1.01% (95%CI: 0.63%, 1.38%), 0.66% (95%CI: 0.02%, 1.30%), 1.62% (95%CI: 1.00%, 2.23%) of daily cardiovascular mortality respectively; 1.09% (95%CI: 0.35%, 1.82%), 0.44% (95%CI: -0.29%, 1.16%), 2.75% (95%CI: 1.42%, 4.08%) of daily respiratory mortality respectively. The air pollutants effect varied across different cities. The strongest effect of PM2.5 was current day (excess risk (ER)=1.10%, 95%CI: 0.66%, 1.54%)), the strongest effect of O3 was 2-day lag (ER=1.82%, 95%CI: 0.69%, 2.97%) and the strongest effect of NO2 was 1-day lag (ER=2.09%, 95%CI: 1.34%, 2.83%) of daily non-accidental mortality respectively.
Conclusion:The increases of PM2.5 and NO2 concentration could result in the increases of daily non-accidental mortality, cardiovascular disease mortality and respiratory mortality. O3 could result in the increases of daily non-accidental mortality and cardiovascular disease mortality. The acute effects for non-accidental mortality from high to low were NO2, PM2.5 and O3, and the strongest effect of PM2.5 was current day. O3 and NO2 had lagged effects.
