Advances in the research of effects of autologous platelet-rich plasma on the treatment of burn wounds
10.3760/cma.j.issn.1009-2587.2018.12.017
- VernacularTitle: 自体富血小板血浆对烧伤创面治疗影响的研究进展
- Author:
Sisi YANG
1
;
Chengzhi XIAO
Author Information
1. Department of Burns and Plastic Surgery, the General Hospital of PLA Tibet Military Area Command, Lhasa 850000, China
- Publication Type:Review
- Keywords:
Platelet-rich plasma;
Burns;
Wound healing;
Cicatrix
- From:
Chinese Journal of Burns
2018;34(12):910-913
- CountryChina
- Language:Chinese
-
Abstract:
Autologous platelet-rich plasma (PRP) is plasma with high concentration of platelet extracted from autologous blood. After activation, growth factors involved in wound healing are released from PRP. Current clinical investigations have demonstrated that the application of PRP seems to enhance the clinical outcome of plastic surgery, oral implantology, maxillofacial region and bone repair, and cardio-thoracic surgery. PRP can stimulate angiogenesis and promote fibroblast proliferation, therefore the application of PRP has shown good results in wound healing. However, up to date there is few current clinical researches on application of PRP on wound healing in burn patients. The application of PRP is not currently standardized, and the effects in burn wounds are poorly understood. This review is to determine if the application of PRP can enhance the clinical outcome of burns and scar formation.
