Comparison of Isoflurane and Propofol Anesthesia on Postoperative Nausea, Vomiting and Recovery after Tonsillectomy in Children.
10.4097/kjae.1997.33.6.1061
- Author:
Seung Hee PARK
;
Jun Hak LEE
;
Ki Nam LEE
;
Jun Il MOON
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Anesthetics, intravenous, propofol;
Anesthetics, volatile, isoflurane;
Surgery, tonsillectomy;
Vomiting, nausea, postoperative
- MeSH:
Adenoidectomy;
Anesthesia*;
Bradycardia;
Child*;
Fentanyl;
Humans;
Incidence;
Intubation;
Isoflurane*;
Nausea;
Postoperative Nausea and Vomiting*;
Postoperative Period;
Propofol*;
Prospective Studies;
Thiopental;
Tonsillectomy*;
Vecuronium Bromide;
Vomiting*
- From:Korean Journal of Anesthesiology
1997;33(6):1061-1066
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The purpose of this study was to compare prospectively two different anesthetic techniques with isoflurane or propofol for postoperative nausea, vomiting and recovery after tonsillectomy in children. METHODS: Sixty children, ASA physical status I, were assigned randomly to one of two groups. In group I, anesthesia was induced with thiopental 5 mg/kg and maintained with isoflurane 1~1.5 vol%. In group P, anesthesia was induced with fentanyl 1 mcg/kg, propofol 2 mg/kg and maintained with propofol infusion 5~10 mg/kg/hr. Both group received vecuronium 0.1 mg/kg for tracheal intubation and were ventilated with 33% O2 in N2O. The time to extubation, time to eye opening, PACU time, incidence and numbers of postoperative nausea and vomiting, and degree of sedation were recorded as well as perioperative complications. RESULTS: There were no significant difference in the duration of anesthesia and PACU time between two groups. The time to extubation and eye opening of group P were significantly shorter than group I (p<0.05). The degree of sedation and incidence of postoperative nausea and vomiting of group P were significantly lower than group I (p<0.05). But the frequency of intraoperative bradycardia was significantly higher in group P than group I (p<0.05). CONCLUSIONS: Propofol-fentanyl anesthesia results in less nausea and vomiting during postoperative period and more rapid recovery compared to isoflurane anesthesia and may be recommended in children undergoing tonsillectomy and adenoidectomy.
