Lymphomatoid gastropathy: one case report and literatures review
10.3760/cma.j.issn.0253-2727.2018.11.013
- VernacularTitle: NK细胞淋巴瘤样胃病一例报告并文献复习
- Author:
Yangzhong ZHOU
1
;
Yan ZHANG
;
Weiyang ZHEN
;
Shengyu ZHANG
;
Jian SUN
;
Zhaohui LU
;
Wei ZHANG
;
Daobin ZHOU
;
Tienan ZHU
Author Information
1. Department of Internal Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinsese Academy of Medical Sciences, Beijing 100730, China
- Publication Type:Journal Article
- Keywords:
Lymphomatoid gastropathy;
NK/T-cell lymphoma;
Gut;
EBER
- From:
Chinese Journal of Hematology
2018;39(11):937-941
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To report the first case of lymphomatoid gastropathy in China, and to demonstrate the clinical characteristics, diagnostic approach, treatment and prognosis in this kind of patients.
Methods:One patient was diagnosed as lymphomatoid gastropathy at Peking Union Medical College Hospital, and her clinical characteristics, lab data, treatment and follow-up outcomes were reviewed.
Results:A case of a 51-year-old female was presented, who underwent esophagogastroduodenoscopy (EGD) due to slight epigastric discomfort. EGD revealed multiple ulcers and erosions. Biopsies showed atypical lymphocytes infiltration with CD3(+), CD56(+), CD20(-), CD8(-), TIA(+), Granzyme B(-) and Ki-67 (75%). Epstein-Barr virus-encoded RNA in situ hybridization was negative. Four months later, repeated EGD examination showed regression of the lesions without specific treatment.
Conclusion:Lymphomatoid gastropathy was a unique disease entity mimicking NK/T-cell lymphomas in pathology, with the quite different profile of treatment and prognosis. It’s important to consider this issue during the differential diagnosis to avoid any excessive treatment.
