The diagnostic value of PLASMIC score in the discrimination between thrombotic thrombocytopenic purpura and disseminated intravascular coagulation
10.3760/cma.j.issn.0253-2727.2018.10.005
- VernacularTitle: PLASMIC积分对血栓性血小板减少性紫癜和弥散性血管内凝血鉴别的临床价值
- Author:
Jie YIN
1
;
Ziqiang YU
;
Danqing KONG
;
Zhaoyue WANG
;
Jun JIN
;
Jun WANG
;
Xueming WANG
;
Jian SU
;
Wei ZHANG
;
Changgeng RUAN
Author Information
1. Jiangsu Institute of Hematology, MOH Key Lab of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou 215006, China
- Publication Type:Journal Article
- Keywords:
PLASMIC score;
Thrombotic thrombocytopenic pupura;
Disseminated intravascular coagulation;
Diagnosis
- From:
Chinese Journal of Hematology
2018;39(10):812-816
- CountryChina
- Language:Chinese
-
Abstract:
Objective:PLASMIC score was evaluated its value in differential diagnosis between the patients with thrombotic thrombocytopenic purpura (TTP) and those with disseminated intravascular coagulation (DIC) .
Method:Twenty-four patients with TTP and 41 cases with DIC were retrospectively analyzed in this study. The platelet count, average red blood cell volume, indirect bilirubin, creatinine and prothrombin time international normalised ratio were collected, and then PLASMIC scores were calculated.
Results:According to the risk classification of PLASMIC score, three (12.5%) TTP patients had moderate risk, and the rest 21 (87.5%) cases had high risk. In DIC patients, 92.7% cases were in low risk group, 4.9% at moderate risk, and only one case had high risk. Of these 65 patients, the sensitivity and the specificity to TTP of the high risk of the scoring system were 87.5% and 97.6%, respectively.
Conclusion:The patients with high risk of PLASMIC score correlated well with clinical TTP diagnosis. The scoring system showed to be an excellent diagnostic model to distinguish TTP patients from those with DIC.
