Effect of excimer laser coronary atherectomy in the interventional treatment of acute coronary syndrome
10.3760/cma.j.issn.0253-3758.2018.10.006
- VernacularTitle: 准分子激光冠状动脉斑块消蚀术在急性冠状动脉综合征介入治疗中应用的效果
- Author:
Xin ZHAO
1
;
Quanmin JING
;
Zhaofeng WANG
;
Yuan HAN
;
Xiaozeng WANG
;
Geng WANG
;
Yaling HAN
Author Information
1. Department of Cardiology, Shenyang General Hospital of People's Liberation Army, Shenyang 110016, China
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
Treatment outcome;
Excimer laser coronary atherectom
- From:
Chinese Journal of Cardiology
2018;46(10):795-798
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of excimer laser coronary atherectomy (ELCA) in the interventional treatment of acute coronary syndrome (ACS).
Methods:This prospective study enrolled 31 patients with ACS who underwent ELCA treatment in our hospital from November 8, 2016 to December 13, 2017. The efficacy and complications of ELCA were observed, and patients were followed up for postoperative observation of major adverse cardiovascular and cerebrovascular events (including target vessel revascularization, stroke, stent thrombosis, coronary artery bypass grafting, and death).
Results:The patients were aged (65.0±10.8) years old and 25 were males (80.6%).There were 5 cases (16.1%) ST-segment elevation myocardial infarction, 3 cases (9.7%) non-ST-segment elevation myocardial infarction, and 23 cases (74.2%) unstable angina in this cohort.There were 9 cases (29.0%) in-stent restenosis, 11 cases (35.5%) saphenous vein graft, 2 cases (6.5%) chronic total occlusive disease, and 4 cases (12.9%) calcification.Two patients with chronic complete occlusive disease and 1 patient with calcified lesion were examined by intravascular ultrasound (IVUS). The other lesions were not examined with IVUS and optical correlation tomography (OCT).The ELCA success rate was 100% (31/31) and the PCI success rate was 100% (31/31).Intraoperative use of 0.9 mm diameter catheters accounted for 38.7% (12/31), 1.7 mm diameter catheters accounted for 32.3% (10/31), and 1.4 mm diameter catheters accounted for 29.0% (9/31).One patient with ST-segment elevation myocardial infarction experienced no reflow of coronary artery during operation. The other 30 patients had no complications such as perforation, small dissection, large dissection, distal occlusion, slow blood flow and collateral occlusion. One cardiac death(3.2%) occurred during the postoperative follow-up of (6.4±1.9) months.
Conclusion:Our preliminary study results indicate that the use of ELCA in the interventional therapy of ACS is safe and effective.