Clinical analysis of 128 cases of cervical lesion diagnosed by multi-point biopsy of colposcopy and endocervical curettage
10.3760/cma.j.issn.0253-3766.2018.07.011
- VernacularTitle: 128例阴道镜检查宫颈多点活检和宫颈管诊刮术诊断宫颈病变的临床价值
- Author:
Beibei LIU
1
;
Yanling ZHU
1
;
Wenhua ZHANG
2
;
Hong ZHANG
1
;
Xinxia WANG
1
;
Xiaojuan YU
1
;
Ping ZHANG
1
;
Jie ZHANG
1
;
Lan WANG
1
;
Shiwen FANG
1
;
Dan LI
1
;
Shiwen ZHEN
1
;
Minhua LU
3
Author Information
1. Department of Gynecologic Oncology, Xuzhou Cancer Hospital, Xuzhou 221000, China
2. Department of Gynecologic Oncology, National Cancer Center/National Clincal Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
3. Department of Pathology, Xuzhou Cancer Hospital, Xuzhou 221000, China
- Publication Type:Clinical Trail
- Keywords:
Cervical lesions;
Colposcopy;
Cervical biopsy;
Endocervical curettage
- From:
Chinese Journal of Oncology
2018;40(7):539-542
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical values of colposcopy and cervical biopsy and/or endocervical curettage (ECC) in the diagnosis of cervical lesion.
Methods:Clinical data of 128 cases of cervical lesion diagnosed by Xuzhou Cancer Hospital from January 23, 2014 to October 11, 2016 were collected and retrospectively analyzed, all patients underwent colposcopy and cervical biopsy and/or ECC.
Results:Among them, the age between 30 to 50 years old were 70 cases, whose transformation zone types of Ⅰ, Ⅱ and Ⅲ were 28 cases (40.0%), 23 cases (32.9%) and 19 cases (27.1%), respectively. The age older than 50 years were 45 cases, whose transformation zone types of Ⅱ and Ⅲ were 1 case (2.2%) and 44 cases (97.8%), respectively. Among the 128 cases of cervical lesions, diagnostic results of colposcopy showed that the chronic inflammation were 57 cases, cervical intraepithelial neoplasia (CIN)Ⅰwere 35 cases, CINⅡor CINⅡ~Ⅲ were 8 cases, CIN Ⅲ were 5 cases and cervical cancer were 23 cases. Alternatively, the pathological results showed that the chronic inflammation were 81 cases, CINⅠwere 17 cases, CINⅡor CINⅡ~Ⅲ were 7 cases, CIN Ⅲ were 5 cases and cervical cancer were 18 cases, respectively. Among the 81 cases of chronic inflammation diagnosed by pathology, 52 cases (64.2%) were consistent with the diagnostic results of colposcopy. Among the 17 cases of low grade squamous epithelial cell lesion (LSIL) diagnosed by pathology, 10 cases were in agree with the diagnostic results of colposcopy. Among the 12 cases of high-grade squamous epithelial cell lesion (HSIL) diagnosed by pathology, 9 cases were concordant with the diagnostic results of colposcopy. Among the 18 cases of cervical cancer diagnosed by pathology, 17 cases were consistent with the diagnostic results of colposcopy.
Conclusions:The type of transformation zone is positively correlated with the age, and it can help to choose biopsy and therapeutic manner. The diagnostic accuracies of HSIL and early stage of cervical cancer by multi-point biopsy of colposcopy and/or ECC are high. The cervical lesions which are difficultly found by direct visualization can be identified by colposcopy, and thus provides objective evidence to determine the therapeutic manner for patients with stage ⅡA of cervical cancer.
