Helicobacter pylori and hepatic encephalopathy
10.3760/cma.j.issn.1007-3418.2018.07.016
- VernacularTitle: 幽门螺杆菌与肝性脑病
- Author:
Jingrun ZHAO
1
;
Jinyan WANG
;
Senlin LI
Author Information
1. Department of Gastroenterology, Liaocheng People’s Hospital, Liaocheng 252000, China
- Publication Type:Review
- Keywords:
Liver cirrhosis;
Hepatic encephalopathy;
Helicobacter pylori;
Ammonia
- From:
Chinese Journal of Hepatology
2018;26(7):553-556
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic encephalopathy (HE) is caused by severe liver disease or portal shunt. Metabolic disorders and central nervous system dysfunctions are the main symptoms of this syndrome. Ammonia is considered to play a central role in the pathogenesis of HE. Helicobacter pylori (H. pylori) have been suggested as a possible source of ammonia production because of its high urease content. However, the relationship between H.pylori and blood ammonia and HE, as well as the therapeutic effect of H.pylori eradication on HE, is inconclusive, and the results are full of contradictions. The aim of this review is to summarize current knowledge on the association of H. pylori with HE and to address the question of whether H. pylori eradication may be beneficial in the management of HE.
