Predictive value for esophageal varices using acoustic radiation force impulse elastography in post-hepatitis B cirrhosis patients
10.3760/cma.j.issn.1007-3418.2018.07.004
- VernacularTitle: 声脉冲辐射力弹性成像技术对乙型肝炎后肝硬化患者食管静脉曲张的预测价值
- Author:
Chunyan WANG
1
;
Jun WEN
1
;
Yonghe ZHOU
1
;
Shuang LI
1
;
Yan ZHANG
1
;
Wei LU
2
;
Jia LI
1
Author Information
1. Tianjin Second People’s Hospital, Tianjin Hepatopathy Research Institute, Tianjin 300192, China
2. Tianjin First Central Hospital, Tianjin Hepatopathy Research Institute, Tianjin 300192, China
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Esophagus;
Varicose veins;
Acoustic radiation force elastography;
Virtual touch tissue quantification
- From:
Chinese Journal of Hepatology
2018;26(7):499-502
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A retrospective analysis of the predictive value of acoustic radiation force impulse (ARFI) elastography for esophageal varices in post-hepatitis B cirrhosis patients.
Methods:124 patients with post-hepatitis B cirrhosis who were admitted to Tianjin Second People’s Hospital from August 2016 to August 2017 were selected. According to the shape of esophageal varices under gastroscopy and the risk of bleeding, patients were divided into 4 groups, none, mild, moderate and severe. In ARFI mode, the VTQ function was used to detect the VTQ values of the liver and spleen. The receiver operating characteristic curve and area under the curve (AUC) were used to evaluate the diagnosis of esophageal varices by VTQ values of the liver and spleen. Analysis of variance was performed on the data between the groups, and χ 2 test was performed for categorical data.
Results:The difference in liver VTQ values between groups were statistically significant (F = 12.623, P < 0.01). There was a statistically significant difference in VTQ values between spleens (F = 9.022, P < 0.01). The liver VTQ predicts that the AUC value of mild esophageal varices in patients with cirrhosis was 0.701 (0.575-0.827); moderate varices was 0.802 (0.701-0.902); severe varices was 0.885 (0.784-0.986). The best cutoff value was 2.235, the specificity was 97.37%, the negative predictive value was 88.10%, and the accuracy was 90.16%. The VTQ value of spleen predicts the AUC value of mild esophageal varices in patients with liver cirrhosis was 0.688 (0.539-0.798); moderate varices were 0.762 (0.651-0.873); severe varices were 0.800 (0.671-0.928). The best cutoff value was 2.885, the specificity was 84.21%, and the negative predictive value was 82.05%.
Conclusion:The application of ARFI elastography in the determination of VTQ values of liver and spleen has certain predictive value for esophageal varices and it might be useful for primary screening of esophageal varices in post-hepatitis B cirrhosis patients.
