The role of transcription factors in differentiation and development of the olfactory epithelium stem cells
10.3760/cma.j.issn.1673-0860.2018.07.014
- VernacularTitle: 嗅上皮干细胞分化、发育中转录因子功能的研究现状
- Author:
He XU
1
;
Caiquan LIANG
1
;
Yaping XU
1
;
Jingping FAN
1
;
Juntian LANG
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, the Naval Medical University Affiliated Chang Zheng Hospital, Shanghai 200003, China
- Publication Type:Review
- Keywords:
Olfactory mucosa;
Stem cells;
Transcription factors
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2018;53(7):550-554
- CountryChina
- Language:Chinese
-
Abstract:
As a sensor of the olfactory system, olfactory epithelium plays an important role in the olfactory system. In addition, olfactory epithelium is the only neuroepithelial epithelium in mammals that can maintain its self-renewal all along. There are of great significance in researching regenerating and repairing neural tissues, transplanting and treatment neural stem cells as well as the occurrence of olfactory disorders and intervention. This review will describe the characteristics of olfactory epithelial stem cells, and mainly summerize the function and significance of each transcription factor in the process of olfactory epithelial stem cell development and differentiation, in order to provide new ideas for the study of olfactory epithelial stem cells.
