Efficacy of staging surgery in pulmonary atresia with intact ventricular septum
10.3760/cma.j.issn.0529-5815.2018.06.008
- VernacularTitle: 室间隔完整型肺动脉闭锁分期治疗策略的疗效分析
- Author:
Jianchuan QI
1
;
Zewei ZHANG
;
Jianhua LI
;
Zhan GAO
;
Liyang YING
Author Information
1. Department of Cardiovascular Surgery, the Children′s Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China
- Publication Type:Journal Article
- Keywords:
Heart defects, congenital;
pulmonary atresia;
Cardiac surgical procedures
- From:
Chinese Journal of Surgery
2018;56(6):427-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the feasibility and efficacy of a staged invasive treatment strategy for the treatment of pulmonary atresia with intact ventricular septum, in the first stage using a catheter-based stent placement, second-stage surgery, and three-stage atrial septal occlusion.
Methods:Totally 19 children with pulmonary atresia with intact ventricular septum were enrolled at Department of Cardiovascular Surgery, the Children′s Hospital of Zhejiang University School of Medicine from January 2009 to December 2017, including 11 male and 8 female patients. The age was (13.8±7.7) days (ranging from 3 to 35 days). The weight was (3.4±0.5) kg (ranging from 2.8 to 4.1 kg). Among them, there were 13 cases of type Ⅱ and 6 cases of type Ⅲ. Regular follow-up visits for patients with stage Ⅰ arterial duct stenting after 1, 3, and 6 months; and routine follow-ups for 1, 3, and 6 months after stage Ⅱ surgery.The t test was used to compare the oxygen saturation between pre-operation and post-operation.
Results:All 19 patients underwent arterial catheterization. The preoperative peripheral oxygen saturation was (64.4±5.3)%, while increased to (86.0±3.0)% after operation (t=16.353, P=0.000). One patient died during follow-up and 2 patients lost follow-up. One patient received stent balloon dilatation due to oxygen saturation decrease.Twelve patients completed the second-stage surgery and 1 case died after surgery. The rest were alive, including 2 cases of double-ventricular correction and 9 cases of semi-ventricular treatment in one room; 2 cases had completed three-stage atrial septal occlusion.
Conclusions:Stage Ⅰ arterial duct stent, stage Ⅱ surgery, and stage Ⅲ atrial septal occlusion to treat pulmonary atresia with intact ventricular septum in children is feasible and effective. The method can be used as the important treatment direction for pulmonary atresia with intact ventricular septum.
