Research progress in pathogenesis, treatment and prognosis of HPV positive head and neck squamous cell carcinoma
10.3760/cma.j.issn.1673-0860.2018.05.014
- VernacularTitle: HPV阳性头颈鳞状细胞癌发病机制、治疗方案及预后研究进展
- Author:
Chunyan SHUI
1
,
2
;
Chao LI
3
;
Wei LIU
1
,
2
;
Yongcong CAI
3
;
Jian JIANG
3
;
Ronghao SUN
3
;
Yuqiu ZHOU
4
;
Gang QIN
1
Author Information
1. Department of Clinical Medicine of Southwest Medical University, Luzhou 646200, Sichuan Province, China
2. Department of Head and Neck Surgery, Sichuan Cancer Hospital, Sichuan Institute of Cancer Research, Sichuan Cancer Prevention and Control Center, Department of Head and Neck Surgery, Affiliated Hospital, Medical College, University of Electronic Science and Technology, Chengdu 610041, China
3. Department of Head and Neck Surgery, Sichuan Cancer Hospital, Sichuan Institute of Cancer Research, Sichuan Cancer Prevention and Control Center, Department of Head and Neck Surgery, Affiliated Hospital, Medical College, University of Electronic Science and Technology, Chengdu 610041, China
4. Department of Clinical Medicine of Chengdu Medical College, Chengdu 610041, China
- Publication Type:Review
- Keywords:
Papillomaviridae;
Carcinoma, squamous cell;
Head and neck neoplasms;
Treatment outcome
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2018;53(5):392-396
- CountryChina
- Language:Chinese
-
Abstract:
Head and neck squamous cell carcinoma (HNSCC) is the sixth common malignant tumors of whole body with a high incidence, which accounts for 90% of the head and neck malignant tumors. Previous studies have shown the risk factors, such as tobacco and alcohol, are related to the occurrence and development of HNSCC. However, recent studies have shown that the non-tobacco and non-alcohol related HNSCC increased year by year. At the same time, more and more studies have shown that HNSCC is related to the infection with human papilloma virus (HPV), and the occurrence and development of HPV-positive HNSCC has own characteristics in epidemiology, pathogenesis, treatment and prognosis. In this paper the research progress for HPV-positive HNSCC is reviewed.
