Persistence of HPV after LEEP Treatment in Cervical Intraepithelial Neoplasia.
- Author:
Hun Young KIM
1
;
Bong Ju LEE
;
In Suk KIM
;
Jung Ho CHOI
;
Heung Gon KIM
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Wonkwang University, Iksan, Korea.
- Publication Type:Original Article
- Keywords:
Cervical intraepithelial neoplasia;
Human papillomavirus;
LEEP
- MeSH:
Cervical Intraepithelial Neoplasia*;
Humans;
Recurrence;
Uterine Cervicitis
- From:Korean Journal of Gynecologic Oncology and Colposcopy
2001;12(2):104-110
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The aim of this study was to identify human papillomavirus (HPV) in cervical intraepithelial neoplasia (CIN) and to evaluate the persistence of HPV after loop electrosurgical excision precedure (LEEP). METHODS: Records of 138 patients with LEEP performed due to cervicitis, CIN I, CIN II and CIN III were reviewed and persistence of HPV were followed up at 3, 6, 9 and 12 month after LEEP treatment from January 1996 to December 1999. RESULTS: Among 202 patients, 138 cases (68.3%) were showed HPV positive before LEEP and histologic findings were showed as cervicitis 20 cases (14.5%), CIN I 23 cases (16.7%), CIN II 31 cases (22.5%) and CIN III 64 cases (46.3%). Persistence of HPV after LEEP treatment were 10.9% (15/138) at 3 month and 2.9% (4/138) at 6 month. However, among 15 cases of persistent HPV, only 5 cases (33.3%) were showed an abnormal Pap smear at 3 month after LEEP. CONCLUSION: Human papillomavirus (HPV) was eliminated over 90% at 3 month after LEEP treatment in CIN. Detection of HPV was helpful to estimate therapeutic effect and to predict the recurrence or persistence of CIN after LEEP treatment.
