Study on Numbers of Cervical Cytology before Diagnosis of Cervical Cancer and Cervical Intraepithelial Neoplasia.
- Author:
Kae Hyun NAM
1
;
Hae Hyeog LEE
;
Kwon Dae KIM
;
Jin Woo LEE
;
Do Hyeong KOO
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University, Korea.
- Publication Type:Original Article
- Keywords:
pap smear;
cervical intraepithelial neoplasia(CIN);
cervical cancer
- MeSH:
Cervical Intraepithelial Neoplasia*;
Cervix Uteri;
Diagnosis*;
Female;
Humans;
Mass Screening;
Primary Prevention;
Secondary Prevention;
Uterine Cervical Neoplasms*;
Uterine Hemorrhage;
Vaginal Smears
- From:Korean Journal of Gynecologic Oncology and Colposcopy
2001;12(2):128-136
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Although a great deal of knowledge accumulated with regard to the causes and epidemiologic features of cervical cancer, primary prevention has not been particularly effective to date. Most efforts with regards of control of cervical cancer have been directed toward secondary prevention with cytologic smears in a screening program. The purpose of this study was to know the cervical smear histories in the women with neoplasia of uterine cervix at present. MATERIALS AND METHOD: Between June, 1993 and October, 1996, seventy women with invasive cervical carcinoma and eighty-seven women with cervical intraepithelial neoplasia(CIN) were interviewed about cervical smear histories to assess the frequencies of past smear at the Soonchunhyang University Hospital. RESULTS: The results were follows: 1. The mean age of the women with invasive cervical cancer and CIN were 55+/-9 and 42+/-11, respectively. 2. Of the 70 cases of cervical cancer, 61%(43/70) has not been screened, compared with 43%(37/87) in cases of CIN. 3. The mean ages at first smear in the cases of previous smear were 42+/-6 of 27 cancers, 37+/-7 of 50 CINs. The gap between the age at the first smear and the age at diagnosis were about 6 years in cases of cervical cancers, about 5 years in cases of CIN. 4. The most common symptom in cervical cancers was vaginal bleeding or postcoital bleeding(57%). Although 13%(9/70) were discovered during screening without symptom in the women with cervical cancers, 58%(52/87) were diagnosed incidently during screening in CIN. 5. Pap smear numbers before diagnosis were strongly associated with age and stage. Among women diagnosed with invasive cancer under the age of 49, 75% had at least one cervical smear. But, all women with cervical cancer over age of 65 have not been screened. Unscreened rates of stage I, II, III, and IV were 34%, 78%, 85% and 83% respectively. 6. Among 38 cases who had undergone radiation therapy, 82%(31/38) had not been screen in contrast to 38%(12/32) in the women who had undergone radical surgery. 7. Among women with previous smears in the cervical cancer, 20%(14/70) have been screened within 1year. CONCLUSION: It is likely to diagnosis cervical cancer who had normal papanicolau smear in recent. So papanicolau smear is examined carefully and other adjunctive test is help to diagnosis cervical cancer exactly, for example cervicography, HPV testing.
