The state of the art research findings on the relationship between chronic periodontitis and Alzheimer's disease: a review
10.3760/cma.j.issn.1002-0098.2018.04.012
- VernacularTitle: 慢性牙周炎与阿尔茨海默病关系的研究现状
- Author:
Xueshen QIAN
1
;
Song GE
1
Author Information
1. Department of Periodontology, Hospital of Stomatology, Zunyi Medical University, Zunyi Guizhou 563000, China
- Publication Type:Review
- Keywords:
Periodontitis;
Periodontopathic microorganisms;
Alzheimer'
s disease;
Inflammation
- From:Chinese Journal of Stomatology
2018;53(4):275-279
- CountryChina
- Language:Chinese
-
Abstract:
Along with the development of periodontal medicine, there is a growing number of evidence showing that periodontitis could influence systemic health. Periodontitis is a chronic inflammatory disease caused by microbial infection mediated by dental plaque. Periodontal pathogenic microorganisms and its toxic products can disseminate through the blood stream or may cause the host immune response, which may lead to pathological changes of cerebral vessels and brain tissues to establish connection with Alzheimer's disease (AD). AD is a progressive neurodegenerative disease characterized by progressive memory loss, language and cognitive dysfunction. This article reviewed the association between chronic periodontitis and AD.
