Research on the relationship between atmospheric inhalable particulate matter and cardiovascular diseases burden in Tianjin
10.3760/cma.j.issn.0253-3758.2018.01.009
- VernacularTitle: 天津市大气可吸入颗粒物与循环系统疾病负担关系的研究
- Author:
Qiang ZENG
1
;
Pei LI
;
Yang NI
;
Guoxing LI
;
Dezheng WANG
;
Xiaochuan PAN
;
Guohong JIANG
Author Information
1. Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China
- Publication Type:Journal Article
- Keywords:
Cardiovascular diseases;
Cerebrovascular disorders;
Cost of illness;
Death;
Years of life lost;
Thoracic particulate matter
- From:
Chinese Journal of Cardiology
2018;46(1):50-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the association between atmospheric inhalable particulate matter (PM10) concentration and cardiovascular diseases burden in Tianjin.
Methods:The data on daily mean concentrations of main pollutants (PM10, nitrogen dioxide(NO2) and sulfur dioxide(SO2)), meteorological factors (temperature and relative humidity) and population death monitoring data in Tianjin, from January 1, 2001 to December 31, 2010, were collected and analyzed in this study. The death counts and years of life lost were simultaneously used as the indicators of disease burden. The generalized additive model was used to assess the associations between PM10 and daily death counts and years of life lost due to cardiovascular system diseases in Tianjin by adjusting the confounding factors such as long-term trend, seasons, meteorological factors and other factors related to the long-term variability.
Results:The daily average concentration of PM10 was 117.6 μg/m³ in Tianjin during 2001 to 2011. The daily average number of deaths of cardiovascular system diseases, cerebrovascular diseases and ischemic heart diseases in Tianjin were 38.4, 14.8 and 17.2 people respectively, and the daily average years of life lost were 776.8, 306.5 and 326.1 person years respectively. The effects of PM10 on the daily death counts of the three diseases categories were statistically significant (all P<0.01) in Tianjin and the maximum effect occurs at the moment when PM10 was at moving average concentration of today and lagged 1-day (Lag01). The effects of decreasing order were ischemic heart diseases, cardiovascular system diseases and cerebrovascular diseases, excess risks were 0.53% (95% CI 0.35%-0.71%), 0.40% (95%CI 0.28%-0.53%) and 0.38% (95%CI 0.19%-0.56%). The effects of atmospheric PM10 on the years of life lost of the three diseases were also statistically significant on the different lag days (all P<0.01) in Tianjin and the maximum effect of PM10 appeared in Lag01. The effects from the largest to the lowest were 2.86 (95%CI 1.79-3.93) person years for cardiovascular system diseases, 1.59 (95%CI 0.95-2.23) person years for ischemic heart diseases and 1.07 (95%CI 0.43-1.71) person years for cerebrovascular diseases, respectively. In multi-pollutant models, after controlling SO2, the effect of PM10 on the daily life loss of above 3 kinds of diseases was higher than that of single pollutant model. In contrast, after controlling SO2 or SO2 with NO2, the effect was lower. After controlling NO2, the effect of PM10 on the daily life loss of cerebrovascular disease was no longer statistically significant (P>0.05).
Conclusions:Exposure to atmospheric PM10 can significantly increase the cardiovascular diseases burden in Tianjin, especially for ischemic heart diseases. These results suggested that particular attention should be paid to reduce the exposure to atmospheric inhalable particulate matter for patients with ischemic heart diseases.
