Pulmonary Tumor Thrombotic Microangiopathy Associated with Advanced Gastric Cancer Successfully Treated with Chemotherapy.
10.12771/emj.2014.37.2.146
- Author:
Seung Hyun YOO
1
;
Kwonoh PARK
;
Ji Yeon HONG
;
Ji Yeon KIM
;
Jang Won PARK
;
Yong Won PARK
;
Kyung Hun LEE
;
Kyung So JEON
Author Information
1. Department of Internal Medicine, KEPCO Medical Center, Seoul, Korea. parkkoh@daum.net
- Publication Type:Case Report
- Keywords:
Pulmonary tumor thrombotic microangiopathy;
Stomach neoplasms;
Pulmonary hypertension;
Chemotherapy
- MeSH:
Adult;
Ants;
Arterioles;
Death, Sudden;
Diagnosis;
Drug Therapy*;
Dyspnea;
Female;
Heart Failure;
Humans;
Hypertension, Pulmonary;
Pulmonary Artery;
Stomach Neoplasms*;
Thrombotic Microangiopathies*
- From:The Ewha Medical Journal
2014;37(2):146-151
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pulmonary tumor thrombotic microangiopathy (PTTM) is an uncommon and fatal malignancy-related pulmonary complication characterized by fibrocellular intimal proliferation of small pulmonary arteries and arterioles. It causes marked pulmonary hypertension, right-side heart failure, and sudden death. Diagnosis of PTTM is extremely difficult while the patient is alive. Here, we report a 44-year-old woman who presented with complaining of progressing dyspnea and pulmonary hypertension but with no history of cancer. She was diagnosed with PTTM caused by advanced gastric cancer ante mortem and was treated effectively with chemotherapy.