Progress in diagnosis and treatment of radioactive iodine-refractory differentiated thyroid carcinoma
10.3760/cma.j.issn.1673-0860.2017.12.020
- VernacularTitle: 碘难治性分化型甲状腺癌诊治进展
- Author:
Zhen ZHAO
1
;
Guohua SHEN
1
;
Yuhao LI
1
;
Ke ZHOU
1
;
Huawei CAI
1
Author Information
1. Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu 610041, China
- Publication Type:Review
- Keywords:
Thyroid neoplasms;
Iodine radioisotopes;
Diagnosis;
Treatment
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(12):956-960
- CountryChina
- Language:Chinese
-
Abstract:
The radioactive iodine-refractory differentiated thyroid carcinoma (RIR-DTC) is a complex process that involves multiple genetic changes and multiple signaling pathways.Radionuclide imaging, genomics and proteomics are effective to clarify the mechanism and helpful in clinical diagnosis and therapy.The treatment of RIR-DTC includes the removal of distant metastases, drug therapy, external radiotherapy and radiofrequency ablation.This review mainly focuses on the pathogenesis, diagnosis and treatment of RIR-DTC.
