Diagnostic value of narrow-band imaging in detection of recurrent nasopharyngeal carcinoma

Jinyuan SI; Jingjin Weng; Benjian Zhang; Guiping Lan; Yong Yang; Bo Huang; Yongli Wang; Ying Qin; Bing LI; Xing Han; Weiming Xiong; Yongfeng SI

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Diagnostic value of narrow-band imaging in detection of recurrent nasopharyngeal carcinoma

VernacularTitle: 窄带成像技术在复发鼻咽癌中的诊断价值
Author: Jinyuan SI ¹ ; Jingjin WENG ¹ ; Benjian ZHANG ¹ ; Guiping LAN ¹ ; Yong YANG ¹ ; Bo HUANG ¹ ; Yongli WANG ¹ ; Ying QIN ¹ ; Bing LI ¹ ; Xing HAN ¹ ; Weiming XIONG ¹ ; Yongfeng SI ¹
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1. Department of Otorhinolaryngology Head and Neck Oncology, People′s Hospital of Guangxi Zhuang Autonomous Region, 530021 Nanning, China
Publication Type:Journal Article
Keywords: Nasopharyngeal neoplasms; Stroboscopy; Recurrence
From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2017;52(12):895-899
CountryChina
Language:Chinese
Abstract: Objective:To evaluate the diagnostic value and feasibility of narrow-band imaging in detection of recurrent nasopharyngeal carcinoma (NPC).
Methods:One thousand three hundred and sixty-four NPC patients who had completed NPC treatment were enrolled. All patients were followed-up with imaging, serological examination of EB virus and nasopharyngeal endoscopy(WL and NBI mode), in which (1) both white light (WL) and NBI modes were done; (2) positive endoscopic patients were given nasopharyngeal biopsy; (3) using histologic finding as criterion standard, the sensitivity, specificity, accuracy and Yonden′s index of two modes were compared. Kappa index was used to evaluate the consistency between the two modes and pathological results respectively; (4) the positive rates of WL and NBI in patients with early recurrent (stage Ⅰ+ Ⅱ) were compared.
Results:A total of 265 cases were suspected as having recurrent lesions by endoscopy in WL mode and 68 cases of them were pathologically diagnosed as having NPC; and 82 cases were suspected as having recurrent lesions by endoscopy in NBI mode and 74 cases of them were pathologically diagnosed as having NPC. The sensitivity, specificity, accuracy and Yonden′s index of WL mode were 91.89%, 0, 25.09% and -0.0811, respectively, with a kappa of -0.045; the sensitivity, specificity, accuracy and Yonden′s index of NBI mode were 100.00%, 95.94%, 97.05% and 0.9594, respectively.
Conclusion:NBI has higher sensitivity, specificity, early diagnosis rate and Yonden′s index than WL.