Ryan index for detection of laryngopharyngeal reflux diseases
10.3760/cma.j.issn.1673-0860.2017.12.002
- VernacularTitle: Ryan指数在诊断咽喉反流性疾病中的探讨
- Author:
Wei WU
1
,
2
;
Gang WANG
1
,
2
;
Lei WANG
1
;
Hongdan LIU
1
;
Qi WANG
3
;
Xiaohang XU
4
;
Ruiying DING
1
;
Bingxin XU
1
;
Haolun HAN
1
;
Ying ZHOU
1
;
Jing GONG
1
;
Hongnan WANG
1
;
Baowei LI
1
;
Zhezhe SUN
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing 100101, China
2. State Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, Beijing 100101, China
3. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100101, China
4. Molecular Biology Research Laboratory, Johns Hopkins University, Baltimore 21218, USA
- Publication Type:Journal Article
- Keywords:
Laryngopharyngeal reflux;
Esophageal pH monitoring;
Sign and symptoms
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(12):885-889
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the utility of pharyngeal pH monitoring which positive standard is Ryan index in diagnosis of laryngopharyngeal reflux disease.
Methods:In a retrospective study, clinical data of 590 patients who had symptoms laryngopharyngeal reflux disease from February 2016 to March 2017 were analyzed. All patients were received electronic laryngoscopy, assessment of reflux symptom index(RSI) and reflux finding score(RFS), and pharyngeal pH monitoring. SPSS 19.0 software was used to analyze the date.
Results:There were 94 patients whose Ryan index were positive(15.93%). Among the 94 patients, 70 were positive during upright, 12 during supine and 12 during both upright and supine. There were 40 patients(6.78%)with pH decline events related to symptoms, while those Ryan index were normal. There were 536(90.85%), 417(70.68%), 233(39.49%) and 117(19.83%) patients with pH<6.5, pH<6.0, pH<5.5 and pH<5.0 events respectively. The positive rate of RSI, RFS, RSI and RFS, RSI or RFS were 44.24%, 16.78%, 7.12%, 53.90% respectively. The RFS score in Ryan index positive group was higher than that in Ryan index negative group[(8.2±2.4) vs (4.0±2.9), u=5.424, P<0.05], while the RSI score in Ryan index positive group was not statistically different from that in Ryan index negative group[(11.3±6.2) vs (12.7±5.8), t=1.247, P=0.167].
Conclusions:Pharyngeal pH monitoring is an objective and non-invasive method which can reflect laryngopharyngeal reflux directly. However, with the Ryan index as a criterion for the diagnosis of laryngopharyngeal reflux disease, partial patients may be missed. Further studies are needed to obtain more accurate and objective laryngopharyngeal pH statistical index for diagnosis of laryngopharyngeal reflux disease.
