Positions of the implanted stimulating electrodes for artificial facial nerve for inducing contraction of the orbicularis oris muscle in rabbit with peripheral facial paralysis
10.3760/cma.j.issn.1673-0860.2017.11.008
- VernacularTitle: 人工面神经诱发面神经麻痹兔口轮匝肌收缩刺激电极植入位置的研究
- Author:
Dongyue XU
1
,
2
;
Ningjun ZHAO
3
;
Yanxia ZHAO
3
;
Dan LUO
3
;
Yajing SUN
3
;
Keyong LI
1
Author Information
1. Department of Otorhinolaryngology Head and Neck Surgery, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China
2. Department of Otorhinolaryngology, Affiliated Hospital of Chifeng University, Chifeng 024050, China
3. Department of Otorhinolaryngology Head and Neck Surgery, Shanghai General Hospital of Shanghai Jiaotong University, Shanghai 200080, China
- Publication Type:Journal Article
- Keywords:
Facial paralysis;
Artificial facial nerve;
Microelectrodes;
Electric stimulation
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(11):841-845
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the optimal positions of the implanted stimulating eletrodes for artificial facial nerve (AFN) for inducing contraction of the orbicularis oris muscle (OOM) in rabbit with peripheral facial paralysis.
Methods:According to the four microelectrodes of the AFN stimulating side, four modes of the implanted positions were divided. In line with different modes, the electrodes were implanted into the affected OOM of the rabbits with unilateral peripheral facial paralysis. AFN output electric stimulation to induce contraction of the affected OOM with uniform stimulating frequency and pulse length in vitro. Then compared the stimulus threshold amplitude and the peak amplitude separately among different modes by SAS 9.3 version statistical software.
Results:The differences of the stimulus threshold amplitude and the peak amplitude had no statistically significant separately between the first mode and the second mode (P>0.05), but there were statistically significant differences between the third mode and the fourth mode (P<0.05). Both kinds of the amplitudes were approximated between the first mode and the second mode respectively, and higher than those in the third mode or the fourth mode. Furthermore, both kinds of the amplitudes in the fourth mode were higher than those in the third mode.
Conclusions:The microelectrodes of the AFN stimulating lateral are implanted into the upper lip with a public microelectrode and an output microelectrode, into the lower lip with an output microelectrode, and into the way, which is located to the angle 40° to 45° about the line joining between the midpoint of the ipsilateral auricle root and the corner of the mouth with an output microelectrode. This is the third positional mode which requires lowest effective stimulus current intensity. Thus the mode is suitable as the optimal placement programme.
