Analysis of clinical features in patients with pneumoconiosis complicated with pulmonary emphysema
10.3760/cma.j.issn.1001-9391.2017.11.018
- VernacularTitle: 尘肺病并发肺气肿患者临床特点分析
- Author:
Xin LI
1
;
Weirong DAI
;
Li LI
;
Wenfeng LIU
;
Zhongxing YANG
;
Lei XIE
Author Information
1. Hunan Institute of Occupational Disease Prevention and Treatment
- Publication Type:Journal Article
- Keywords:
Pneumoconiosis;
Emphysema;
Pulmonary fibrosis
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2017;35(11):865-867
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical features of pneumoconiosis complicated with pulmo-nary emphysema.
Methods:selected 868 patients with pneumoconiosis were selected from December 2015 to December 2016 in Hunan occupational disease prevention and treatment hospital. Collected the results of high-resolution spiral CT, arterial blood gas, ECG, pulmonary function and MRC score. The subjects were divided into pneumoconiosis complicated with pulmonary emphysema group and simple pneumoconiosis group accord-ing to the results of HRCT. The smoking, MRC score, pulmonary function, blood gas and complications were compared.
Results:A total of 868 patients were enrolled in the study. Emphysema 232 people, accounting for 26.73%. The incidence of emphysema in the first phase of pneumoconiosis was 12.69%, and the incidence rate of emphysema in pneumoconiosis was 17.03%, The incidence of three Stage pneumoconiosis was highest, up to 60.76%, the incidence of emphysema increased with the increase of stages of pneumoconiosis (P=0.000) .The smoking index of pneumoconiosis combined with emphysema group was significantly higher than that of simple pneumoconiosis group (P<0.01) . The MRC score of pneumoconiosis complicated with pulmonary em-physema group was higher than that of simple pneumoconiosis group (P=0.000) . In pneumoconiosis complicat-ed with pulmonary emphysema group the FEV1.0%, FVC%, FEV1.0/FVC, DLCO%, oxygen partial pressure were significantly lower than that of simple pneumoconiosis group (P≤0.05) . The combined rate of Bullae of lung in pneumoconiosis complicated with pulmonary emphysema group was higher than that of simple pneumo-coniosis group (P<0.01) .
Conclusion:pneumoconiosis stage and smoking. Patients with pneumoconiosis com-plicated with pulmonary emphysema had heavier breathing difficulties, more serious pulmonary function and active endurance, the degree of hypoxia is more serious, and had a higher incidence of complications. The pul-monary function of pneumoconiosis complicated with pulmonary emphysema is not consistent with the typical CPFE.
