Smoking Status and Augmentation Index in Korean Male Subjects.
- Author:
Eui Jeong WOO
1
;
Hong Soo LEE
;
Sang Hwa LEE
;
Kyung Won SHIM
;
Sooa KIM
;
Young A OH
;
Myoung Jin LEE
Author Information
1. Department of Family Medicine, Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea. hongslee@ewha.ac.kr
- Publication Type:Original Article
- Keywords:
smoking;
augmentation index;
arterial stiffness
- MeSH:
Cardiovascular Diseases;
Humans;
Male*;
Manometry;
Mortality;
Risk Factors;
Smoke*;
Smoking*;
Vascular Stiffness
- From:Journal of the Korean Academy of Family Medicine
2007;28(10):748-753
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Smoking is a major risk factor of cardiovascular morbidity and mortality. Arterial stiffness has been identified as an important determinant of cardiovascular risk. Augmentation index is an indicator of arterial stiffness, which can be quantified noninvasively. The goal of this study was to assess the effect of current smoking status on augmentation index (AIx) in Korean male subjects. METHODS: A total of 70 males without clinical cardiovascular diseases were studied in this cross sectional study. AIx was measured in 35 current smokers and 35 nonsmokers by recording pressure waveforms using radial applanation tonometry in a SphygmoCor device. RESULTS: Augmentation index was significantly higher in the current smokers (19.4+/-12.9% vs. 9.7+/-12.8%; P<0.05). A multiple regression model confirmed that smoking status was independently associated with arterial stiffness (beta=0.350, P<0.001). CONCLUSION: Current smoking is associated with increased augmentation index, which is a marker of cardiovascular disease. Further studies are required to investigate clinical applications of arterial stiffness.
