Effects of percutaneous nephrolithotomy in the treatment of medullary sponge kidney with calculi
10.3760/cma.j.issn.0529-5815.2017.10.005
- VernacularTitle: 经皮肾镜取石术治疗髓质海绵肾合并结石的效果分析
- Author:
Yang HONG
1
;
Qingquan XU
;
Xiaobo HUANG
;
Zhenjie ZHU
;
Haiyun YE
;
Fengshi ZHANG
;
Qingya YANG
;
Lizhe AN
;
Tao XU
Author Information
1. Department of Urology, Peking University People′s Hospital, Beijing 100034, China
- Publication Type:Journal Article
- Keywords:
Medullary sponge kidney;
Kidney calculi;
Nephrostomy, percutaneous
- From:
Chinese Journal of Surgery
2017;55(10):742-745
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of percutaneous nephrolithotomy (PNL) in the treatment of medullary sponge kidney with calculi.
Methods:A total of 77 patients (91 renal units) of medullary sponge kidney with calculi (MSK group) and 77 patients (77 renal units) with common kidney stone (control group) received PNL at Department of Urology in Peking University People′s Hospital from September 2006 to February 2016 were analyzed retrospectively. The MSK group included 33 males and 44 females with a mean age of (42.1±13.2) years, the mean stone burden was (3.9±1.8) cm. The control group included 36 males and 41 females with a mean age of (45.3±13.0) years, the mean stone burden was (3.6±1.5) cm. The numbers of tracts, the time of operation, the drop of hemoglobin, the change of creatine, the time of hospitalization, the stone free rate and major complications were compared between the two groups. The measurement data and numeration data were compared with t test and χ2 test.
Results:There were no significant differences in sex, age, preoperative urinary tract infection, stone type, and stone burden between the two groups (all P>0.05). The proportion of bilateral renal calculus in MSK group was higher (18.2% vs. 0, χ2=15.400, P=0.000). There were 159 percutaneous channels were established in MSK group while 90 percutaneous channels were established in control group. Compared with the control group, the operation time ((88.1±37.5) minutes vs. (68.5±30.1) minutes, t=3.543, P=0.000) and hospitalization time ((15.1±8.3) days vs. (10.1±3.6) days, t=4.816, P=0.000) were longer, the creatinine level increased ((101.2±62.6) μmol/L vs. (71.3±23.6) μmol/L, t=3.777, P=0.000), the rate of stone free decreased (27.5% vs. 83.1%, χ2=51.840, P=0.000) and the rate of complications increased (29.9% vs. 11.7%, χ2=8.114, P=0.004) in MSK group. There was no statistically difference in hemoglobin drop ((12.5±13.2) g/L vs. (13.0±10.9) g/L, t=-0.260, P=0.795).
Conclusions:Using PNL for patients of MSK with calculi has a lower stone free rate and a higher complications. It is an effective method for patients of MSK with large and complex calculi.
