Prospective association between early adiposity rebound and adolescent development in girls
10.3760/cma.j.issn.0253-9624.2017.09.005
- VernacularTitle: 脂肪重积聚提前与女童青春期发育的关联研究
- Author:
Ying SUN
1
,
2
;
Jiao FANG
;
Rong YANG
;
Yaping LAI
;
Jingjing HU
;
Xiaonan DUAN
;
Puyu SU
;
Yuhui WAN
;
Fangbiao TAO
Author Information
1. Department of Maternal, Child & Adolescent Health, School of Public Health, Anhui Medical University
2. Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei 230032, China
- Publication Type:Journal Article
- Keywords:
Puberty;
Breast;
Body mass index;
Cohort studies;
Adiposity rebound
- From:
Chinese Journal of Preventive Medicine
2017;51(9):796-800
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine possible relations between early adiposity rebound and adolescent development.
Methods:Prospective children cohort from 2 kindergartens selected through clustering convenience sampling method in Anhui Province was established since Sep. 2010. Participants were classified as Cohort 1 (2010), Cohort 2 (2011) and Cohort 3 (2012) according to the recruiting year. Till Sep. 2015, a toal of 802 girls were included in this study, and received follow-up till primary school. During kindergarten period, physical examination was carried out every 3 months, 8 times in total. In primary school, physical examination was carried out annually; till Sep.2015, the cohort 1, 2, 3 took physical examination for 12, 11, 10 times, respectively. Information on household economic status and child physical activity was acquired through parents questionnaire survey, and breast development were assessed through visual inspection and palpation. Adiposity rebound was determined according to Rolland-Cachera's method for each girl. Differences between early adiposity rebound and normal adiposity rebound groups were compared by using t test and χ2 test. Multivariate regression analysis was applied to explore the association between early adiposity rebound and breast development.
Results:The average age of participants was (8.90±0.87) years old and the BMI was (17.48±2.70) kg/m2. The average age at adiposity rebound was (6.16±0.90) years old and the BMI was (15.33±1.82) kg/m2. Premature breast development was found significantly higher in girls in early adiposity rebound group (27.8%, 54/802) than it in normal adiposity rebound group (13.7%) (P<0.001). After current adiposity, age, household economic status, childhood physical activity adjusted, the OR of premature beast development in early adiposity rebound group was 2.41(95%CI: 1.41-4.12).
Conclusion:Early adiposity rebound increases the risk of premature puberty in girls.
