Progress of molecular subtypes of colorectal cancer
10.3760/cma.j.issn.0253-3766.2017.09.001
- VernacularTitle: 结直肠癌分子分型研究进展
- Author:
Zeyang CHEN
1
;
Xin WANG
1
;
Tao WU
1
;
Yucun LIU
1
;
Pengyuan WANG
1
Author Information
1. Department of General Surgery, Peking University First Hospital, Beijing 100034, China
- Publication Type:Review
- Keywords:
Colorectal neoplasms;
Molecular subtype;
Precision medicine
- From:
Chinese Journal of Oncology
2017;39(9):641-645
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the leading causes of morbidity and mortality around the world. Although the staging and classification systems, such as tumor/node/metastasis (TNM) staging, are widely used in clinic, there are some limitations. For example, the patients with the same pathological type, TNM stage and treatment regimen show a completely different prognosis and outcome. In the present, molecular subtyping was concerned for a more precise and accurate staging of colorectal cancer. Herein, we reviewed the literature of the molecular subtypes of colorectal cancer in the past decades. The clinical significance of various molecular subtyping systems was evaluated and compared. It will provide reference for the precision medicine of colorectal cancer in the future.
