Definition and diagnosis of acute-on-chronic liver failure: new knowledge and implication
10.3760/cma.j.issn.1007-3418.2017.09.005
- VernacularTitle: 慢加急性肝衰竭的定义及诊断：新认识及启示
- Author:
Wenting TAN
1
;
Guohong DENG
Author Information
1. Department of Infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing Key Laboratory of Infectious Diseases, Chongqing 400038, China
- Publication Type:Journal Article
- Keywords:
Liver failure;
Hepatitis B, chronic;
Liver cirrhosis
- From:
Chinese Journal of Hepatology
2017;25(9):659-663
- CountryChina
- Language:Chinese
-
Abstract:
Acute-on-chronic liver failure (ACLF) is a common critical and severe syndrome in patients with chronic liver diseases in China and other countries in the Asia-Pacific region. In recent years, both the Eastern and Western experts have defined ACLF as a new type of liver disease manifesting as a high 28-day mortality rate (>30%) and extensive systematic inflammatory response. ACLF has become a hot topic in the field of liver diseases. This article reviews the research advances in the definition and etiological spectrum of ACLF and discusses the inspirations of such new knowledge for future research.
