Long Term Use of Glucocorticoid Induced Osteoporotic Multiple Compression Fractures in Autoimmune Diseases.
10.4078/jkra.2009.16.3.228
- Author:
Ye Soo PARK
1
;
Wan Sik SEO
;
Jae Lim CHO
;
Tae Hwan KIM
Author Information
1. Department of Orthopaedic Surgery, Guri Hospital, Hanyang University College of Medicine, Guri, Korea. hyparkys@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Autoimmune disease;
Steroid;
Osteoporotic vertebral fracture
- MeSH:
Autoimmune Diseases;
Bone Density;
Fractures, Compression;
Hepatitis, Autoimmune;
Humans;
Injections, Intravenous;
Middle Aged;
Osteoporosis;
Vertebroplasty
- From:The Journal of the Korean Rheumatism Association
2009;16(3):228-231
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reduced bone mineral density precedes the development of vertebral fractures in patients under long term glucocorticoid therapy. Osteoporosis is a frequent complication in steroid-dependent patients, and the risk of developing vertebral fractures in these patients is much higher than involutional osteoporosis. We described a 54-year-old patient who presented with autoimmune hepatitis and had a 6-year history of steroid medication. The patient had multiple compression fractures (T10~L5) without trauma, and was treated successfully with multi-level vertebroplasty and an intravenous injection of bisphosphonate without complications.
