Analysis of influencing factors of heart rate deceleration capacity in patients with dilated cardiomyopathy
10.3760/cma.j.issn.0253-3758.2017.09.005
- VernacularTitle: 扩张型心肌病患者心率减速力的影响因素分析
- Author:
Fengyan WANG
1
;
Cao ZOU
;
Hongkai DONG
;
Yichen YANG
;
Meiwen GAO
;
Ru ZHAO
;
Jianling JIN
;
Xiangjun YANG
Author Information
1. Department of Cardiology, First Affiliated Hospital of Soochow University, Suzhou 215006, China
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy, dilated;
Vagus nerve;
Heart rate deceleration capacity
- From:
Chinese Journal of Cardiology
2017;45(9):753-757
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the determinants affecting the heart rate deceleration capacity (DC) in patients with dilated cardiomyopathy (DCM).
Methods:One hundred patients with DCM (DCM group) and 202 healthy subjects (control group) were respectively enrolled. Echocardiography and 24 hours electrocardiogram were performed in all subjects. DC value was compared between the two groups. Multiple regression analysis was made to evaluate the related determinants of DC ((age, sex, echocardiographic parameters including the left atrial diameter (LAD) and left ventricular ejection fraction (LVEF)).
Results:(1) DC value was significantly lower in DCM group than in control group( (4.40±2.03) ms vs. (7.30±1.81) ms, P<0.01), prevalence of DC value≤4.5 ms was significantly higher in DCM group than in control group (62% vs. 6%, P<0.01). (2) DC value in the DCM group decreased in proportion to increasing LAD dimension, DC value was (5.60±2.04) ms, (4.50±2.07) ms and (3.60±1.62) ms (P<0.05) in DCM patients with LAD≤40 mm, 40 mm50 mm, respectively. (3) DC value in the DCM group was negatively related to the LAD (r=-0.366, P<0.01), positively related to the LVEF (r= 0.241, P<0.01), but not related with age and sex. Multiple factors regression analysis showed that increased LAD was related to the reduced DC values independtly.
Conclusion:DC value of the patients in the DCM group is decreased, which indicate the decrease of the vagus nerve tension, and increased LAD is related to the reduced DC value independtly in DCM patients.
