A Case of Chronic Inflammatory Demyelinating Polyneuropathy in a Patient with Systemic Lupus Erythematosus.
10.4078/jkra.2009.16.3.243
- Author:
Ki Won MOON
1
;
Yeong Wook SONG
;
Ran SONG
;
Chan Young YUN
;
Jae Ki KOH
;
Jin Hyun KIM
;
Eun Young LEE
;
Eun Bong LEE
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ysong@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Chronic inflammatory demyelinating polyneuropathy;
Systemic lupus erythematosus
- MeSH:
Abdominal Pain;
Cyclophosphamide;
Demyelinating Diseases;
Extremities;
Female;
Fever;
Foot;
Hand;
Humans;
Hypesthesia;
Immunization, Passive;
Lupus Erythematosus, Systemic;
Neural Conduction;
Polyneuropathies;
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating;
Reflex, Stretch;
Sensation
- From:The Journal of the Korean Rheumatism Association
2009;16(3):243-247
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chronic inflammatory demyelinating polyneuropathy (CIDP) is characterized by symmetrical weakness, impaired sensation, absent or diminished tendon reflexes, an elevated cerebrospinal fluid protein level and nerve-conduction studies that show demyelination. The occurrence of CIDP in patients with systemic lupus erythematosus (SLE) has been rarely reported. We experienced a case of a 33 year-old woman with SLE and she presented with fever, abdominal pain, a tingling sensation of both of her hands and feet, and symmetrical weakness in both the proximal and distal extremities. Her symptoms had persisted for over 1 months before she visited our department. The CSF examination showed an elevated protein level and the nerve conduction studies revealed demyelination. Her symptoms showed minimal improvement with high dose steroid and immunoglobulin therapy, but she responded to cyclophosphamide therapy.
