Association between the time of sedentary behaviors and risk of type 2 diabetes
10.3760/cma.j.issn.0253-9624.2017.08.014
- VernacularTitle: 河南农村1 227名成年人静息活动时间与2型糖尿病发病风险的关联研究
- Author:
Yuanyuan SHI
1
;
Yuqian LI
;
Jinjin WANG
;
Chongjian WANG
;
Jingzhi ZHAO
;
Lei YIN
;
Jingjing FAN
;
Wen ZHOU
;
Linlin LI
Author Information
1. College of Public Health, Zhengzhou University, Zhengzhou 450000, China
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Case-control studies;
Time of sedentary behaviors
- From:
Chinese Journal of Preventive Medicine
2017;51(8):734-739
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between the time of sedentary behaviors and the risk of type 2 diabetes mellitus (T2DM) among rural adults in Henan Province.
Methods:A total of 1 227 adults from Houzhai village in Zhengzhou City and Qiaomiao village in Jiaozuo City in Henan Province were randomly selected to participate in the survey; each of them finished a questionnaire and accepted physical examination and test of biochemical indicators. The participants were divided into case and control groups according to whether suffering from T2DM. A Pearson linear correlation and linear regression model analysis were used to investigate the relevance between the time of sedentary behaviors and fasting plasma glucose (FPG); meanwhile, a multi factor logistic regression model was used to analyze the relationship between the time of sedentary behaviors and T2DM.
Results:The average FPG level among the participants was (5.4±2.5) mmol/L, and the average time of sedentary behaviors was (234.5±156.5) min per day. The prevalence rate of T2DM in subgroups whose time of sedentary behaviors were separately 0-<2.5, 2.5-<4.5, 4.5-<6.5 and ≥6.5 h/day were 15.8% (72/457), 19.3% (73/379), 16.7% (35/210) and 20.4% (37/181), respectively. There was a linear regression relationship between the time of sedentary behaviors(x) and FPG(y), the regression equation was: y=5.081+0.001x (t=3.01, P=0.003). Logistic regression model analysis showed that participants whose time of sedentary behaviors ≥6.5 h/day had significantly higher risk of T2DM than those whose time of sedentary behaviors between 0-2.4 h/day (OR=1.77, 95%CI: 1.11-2.81) after age and gender adjusted. However, the associations only exist in males and adults ≥50 years old according to sex and age stratification. It showed that participants with sedentary time ≥6.5 h/day had significantly higher risk of T2DM than those with sedentary time between 0-<2.5 h/d, with the corresponding OR (95%CI) at 2.34 (1.21-4.52) and 2.22 (1.19-4.16), respectively.
Conclusion:The prolonged sedentary time is a risk factor of type 2 diabetes. After stratification by gender and age, the correlation only found in males and adults aged ≥50 years old.
