Progress of dopamine in obstructive sleep apnea hypopnea syndrome
10.3760/cma.j.issn.1673-0860.2017.07.018
- VernacularTitle: 多巴胺与睡眠呼吸障碍研究进展
- Author:
Zhiyuan SONG
1
;
Hongliang YI
1
Author Information
1. Department of Otorhinolaryngology, Shanghai Jiao Tong University Affiliated Sixth People′s Hospital, Otorhinolaryngology Institute of Shanghai Jiao Tong University, Shanghai 200233, China
- Publication Type:Review
- Keywords:
Sleep apnea, obstructive;
Parkinson disease;
Dopamine;
Hypoglossal nerve
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(7):549-551
- CountryChina
- Language:Chinese
-
Abstract:
The etiology and pathogenesis of sleep obstructive apnea hypopnea syndrome (OSAHS) is not yet definitive, evidence shows that the dysfunction of pharyngeal nerve and the atonia of the muscle innervated by these nerve could play an important role in the progress of OSAHS. Dopamine is a neurotransmitter in the central nervous system which significantly affects the sleep-awake regulation. So far mounting evidence shows that dopamine has a potential role in the modulation of hypoglossal nucleus. The progress of dopamine in obstructive sleep apnea hypopnea syndrome is reviewed in this article.