Clinicopathological characteristics of papillary thyroid microcarcinoma and risk factors for central lymph node metastasis
10.3760/cma.j.issn.1673-0860.2017.06.006
- VernacularTitle: 甲状腺微小乳头状癌临床病理特征及中央区淋巴结转移危险因素分析
- Author:
Yanle WU
1
;
Jinming SUN
1
;
Jinjun ZHANG
1
;
Qiuxia CUI
1
;
Weihong ZHENG
1
;
Xingrui LI
1
Author Information
1. Department of Thyroid and Breast Surgery, Affiliated Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Carcinoma, papillary;
Pathology, clinical;
Lymphatic metastasis;
Risk factors
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(6):426-429
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinicopathological characteristics of papillary thyroid microcarcinoma (PTMC) and risk factors for central lymph node metastasis(CLNM) in PTMC.
Methods:The data of 900 patients with PTMC initially treated in our hospital from January 2004 to December 2015 were retrospectively analyzed. Chi-square test and Logistic regression analysis were performed to determine the risk factors for CLNM.
Results:CLNM affected 162 (22.9%) of 707 patients treated with central lymph node dissection. Age, maximum tumor size, multifocality, bilaterality, and extracapsular spread (ECS) were significantly correlated with CLNM (all P<0.01). Age<45 years, maximum tumor size>5 mm, multifocality, bilaterality, and extracapsular spread were independently correlated with CLNM.
Conclusion:A prophylactic central lymph node dissection should be considered in PTMC patients with age<45 years, maximum tumor size>5 mm, multifocality, bilaterality, and extracapsular spread.
