Clinical features of postoperative cervical lymph nodes recurrence in papillary thyroid carcinoma
10.3760/cma.j.issn.1673-0860.2017.06.004
- VernacularTitle: 甲状腺乳头状癌颈部复发转移性淋巴结临床特征分析
- Author:
Yuqin HE
1
;
Bin ZHANG
1
;
Yabing ZHANG
1
;
Zhengang XU
1
;
Pingzhang TANG
1
Author Information
1. Department of Head and Neck Surgery, National Cancer Center/Cancer Hospital, Beijing 100021, China
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Carcinoma, papillary;
Recurrence;
Lymphatic metastasis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(6):416-420
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyse the postoperative metastasis or recurrence of cervical lymph nodes in individual neck levels for papillary thyroid carcinoma and to evaluate the outcomes and complications of re-surgery.
Methods:A retrospective cohort study of 259 patients who underwent lymph node dissection for PTC relapse from January 2010 to June 2011. Lymph node metastases in each of neck levels were detected, postoperative complications were evaluated, and the patients were followed up with examining thyroglobulin levels to assess the therapeutic effect.Continuous variables were compared with t test.Categorical variables were compared with Fisher′s exact test.
Results:Lymph node metastasis was found in 259 cases and lymph node metastasis rates in levels Ⅱ, Ⅲ, Ⅳ, Ⅴ and Ⅵ were 43.2%, 50.2%, 45.6%, 8.1% and 59.1% respectively. In 44 cases received the neck dissection of level Ⅱ, the metastasis rates in the levels Ⅱa and Ⅱb were respectively (52.3% vs 18.2%, P=0.887). Recurrence in unilateral lateral neck was more common than that in bilateral lateral neck (73.1% vs 20.6%, P<0.001). The lymph nodes in lateral neck were more likely to metastasize than those in central region (80.7% vs 59.1%, P<0.001). There were 47 cases (18.1%) had postoperative complications, including 10 cases with permanent hypocalcemia.
Conclusions:The scope of re-operation for neck metastasis or recurrence in papillary thyroid carcinoma should include the dissection of levels Ⅱ-Ⅳ and Ⅵ. The incidence of postoperative complications for re-surgery is high, and re-surgery should be performed by experienced surgeon.
