Relationship of lipid accumulation product with hypertension and diabetes among Beijing residents study
10.3760/cma.j.issn.0253-9624.2017.05.009
- VernacularTitle: 北京市常住居民脂质蓄积指数与高血压、糖尿病的关系
- Author:
Yuanyuan SHEN
1
;
Jichun CHEN
;
Gang LI
;
Jie CAO
;
Jianxin LI
;
Jianfeng HUANG
;
Dongfeng GU
Author Information
1. Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
- Publication Type:Journal Article
- Keywords:
Cross-sectional studies;
Hypertension;
Diabetes mellitus;
Body mass index;
Lipid accumulation product
- From:
Chinese Journal of Preventive Medicine
2017;51(5):415-420
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the lipid accumulation product (LAP) formula for Beijing adults and to investigate the relationship between lipid accumulation product and hypertension, as well as diabetes.
Methods:A cross-sectional study with a representative sample of 19 606 residents in Beijing aged 18-79 years was conducted in 2011. The sex-specific hypothetical minimum waist circumference (WC) was calculated in order to obtain the more applicable LAP formula. Multivariate logistic regression was used to analyze the associations of LAP, combination of LAP and body mass index (BMI) with hypertension and diabetes.
Results:The LAP formula for Beijing adults was established as follows: LAP (male)= (WC-61.3) × TG, and LAP (female)= (WC-55.6) × TG. There was an obvious trend of increased risk of hypertension and diabetes with an increment in the tertiles of the LAP both in men and women. The OR (95%CI) for hypertension in the group with highest tertile LAP was 3.62 (3.11-4.22) in men, and 5.79 (4.84-6.93) in women, compared with the lowest tertile group, respectively; and the corresponding OR for diabetes was 3.47 (2.73-4.41) in men, and 4.10 (2.90-5.80) in women, respectively. Compared with the lowest tertile of LAP and normal BMI group, the OR (95%CI) for hypertension in the highest tertile of LAP and obesity group was 6.79 (5.50-8.37) in men, and 9.75 (7.76-12.25) in women, respectively; while the corresponding value for diabetes was 3.97 (2.87-5.49) in men, and 4.13 (2.78-6.14) in women, respectively.
Conclusion:The elevated level of LAP was associated with an increased risk of hypertension and diabetes among Beijing adults. LAP could be an important predictor for hypertension and diabetes.
