Study of susceptibility weighted imaging on MR and pathologic findings to distinguish benign or malignant soft tissue tumor
10.3760/cma.j.issn.0253-3766.2017.05.006
- VernacularTitle: 磁敏感加权成像鉴别良恶性软组织肿瘤的价值及其与病理对照分析
- Author:
Jie LIU
1
;
Yong CHEN
1
;
Xuemei BAO
1
;
Xiaoli LING
1
;
Jianping DING
1
;
Zekun ZHANG
2
Author Information
1. Department of Radiology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China
2. Department of Radiology, the Third Hospital of hebei Medical University, Shijiazhuang 050051, China
- Publication Type:Clinical Trail
- Keywords:
Susceptibility weighted imaging;
Neoplasms;
Soft tissue;
Differential diagnosis
- From:
Chinese Journal of Oncology
2017;39(5):350-354
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the diagnostic performance of susceptibility weighted imaging (SWI)in distinguishing benign or malignant soft tissue tumor, and to study pathological observation.
Methods:Sixty-eight patients with soft tissue tumor, who received no previous treatment or invasive examination, received routine preoperative MRI examination and SWI scanning. The graduation and distribution of intratumoral susceptibility signal intensity(ITSS) and proportion of tumor volume were observed.The pathological results were also included for comparative analysis.
Results:Fourty of 68 patients were benign and 28 were malignant. 72.5% (29/40) patients with benign soft tissue tumors were ITSS grade 1 and ITSS grade 3 (hemangioma). 89.3%(25/28) patients with malignant soft tissue tumors were ITSS grade 2 and ITSS grade 3. The difference was statistically significant (P<0.01). The distribution of ITSS in patients with benign soft tissue tumors was dominated by peripheral distribution and diffuse distribution (hemangioma), accounting for 90.0% (36/40). The distribution of ITSS in patients with malignant soft tissue tumors mainly distributed in the central region, accounting for 78.6% (22 /28). The difference was statistically significant (P<0.01). The proportion of tumor volume occupied by ITSS in benign soft tissue tumors was <1/3 and> 2/3 (hemangioma), accounting for 90.0% (36/40). The volume of malignant soft tissue tumors were predominantly <1/3 , accounting for 82.1% (23/28). The difference was statistically significant (P<0.01).
Conclusion:SWI is sensitive in displaying the vein and blood metabolites in soft tissue lesions, which is helpful for the differential diagnosis of benign and malignant tumors in soft tissue.
