Research advances in epithelial - mesenchymal transition in hepatocellular carcinoma

VernacularTitle: 肝细胞癌相关的上皮间质转化研究进展
Author: Jingxia YU ¹ ; Ting LIU ; Qinkai LI ; Mingyi XU ; Lungen LU
Author Information

1. Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 201600, China
Publication Type:Review
Keywords: Carcinoma, hepatocellular; Epithelial - mesenchymal transition; Signaling pathway
From: Chinese Journal of Hepatology 2017;25(5):389-392
CountryChina
Language:Chinese
Abstract: Epithelial-mesenchymal transition (EMT) is a process by which epithelial cells lose their own features and become mesenchymal cells, and more and more studies have shown that EMT plays an important role in the invasion and metastasis of hepatocellular carcinoma (HCC). This article reviews the signaling pathways involved in the progression of HCC and molecules involved in the regulation of EMT, in order to provide a new direction for the treatment of HCC.