Hepatitis B seroepidemiological investigation among healthy people of Tianmen city
10.3760/cma.j.issn.1003-9279.2017.05.013
- VernacularTitle: 天门市健康人群乙型肝炎血清流行病学调查分析
- Author:
Liming WEI
1
;
Jiachun TAO
;
Jiaoping ZHANG
Author Information
1. Tianmen Center for Disease Control and Prevention, Tianmen 431700, China
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Serology;
Epidemiological investigation
- From:
Chinese Journal of Experimental and Clinical Virology
2017;31(5):438-440
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the hepatitis B (HB) infection status among healthy people of Tianmen city, and to evaluate the effect of undertaking vaccination against hepatitis B, and to direct the work of HB prevention and control.
Methods:Multi-stage random sampling was applied to 5 among the 27 townships of Tianmen city, 398 and 1 756 persons of age between 1 and 59 years were sampled in 2006 and 2012, respectively, blood samples were collected, HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were tested by ELISA; database was established with Epidata 3.1 and data were processed and analyzed by SPSS 13.0.
Results:The infection rates among the healthy people aged between one year and 59 years in 2006 and 2012 were 38.44% and 19.25% respectively with significant difference (χ2=67.92, P=0.000); HBsAg carrying rate was 8.04% and 6.09% without statistical significance (χ2=2.04, P=0.15). However, Results of age groups between 1 to 8 years old, 9 to 19 years old, and 20 to 59 years old in the same year showed that the HBsAg positive rates had very significant difference (χ2=24.56, P=0.000 in 2006; χ2=78.29, P=0.000 in 2012), and that the HBsAb positive rates were 72.86% and 57.23% with significant difference (χ2=26.96, P=0.000), while the HBeAg positive rates were 1.76% and 0.63%, and the HBeAb positive rates were 6.03% and 4.61%, and the HBcAb positive rates were 38.44% and 19.02%.
Conclusions:In 2012, the HB infection status among healthy people of Tianmen city declined sharply, the number of people infected infected with HB decreased as compared with 6 years before. Undertaking HB vaccination and the HB prevention and control strategies protected the susceptible population, and remarkable achievements were obtained.
