Prediction of occult carcinoma in contralateral nodules based on the ultrasonic features of unilateral papillary thyroid carcinoma
10.3760/cma.j.issn.1673-0860.2017.04.004
- VernacularTitle: 甲状腺乳头状癌的超声特征与对侧腺叶合并隐匿癌的关系探讨
- Author:
Liming YANG
1
;
Qiang LI
1
;
Bowen ZHAO
1
;
Jianghong LYU
1
;
Haishan XU
1
;
Lilong XU
1
;
Shiyan LI
1
;
Li GAO
2
;
Jiang ZHU
1
Author Information
1. Department of Diagnostic Ultrasound, Sir Run Run Shaw Hospital of Zhejiang University College of Medicine &Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, China
2. Department of Head and Neck Surgery, Sir Run Run Shaw Hospital of Zhejiang University College of Medicine &Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, China
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid neoplasms;
Carcinoma, papillary;
Risk factors
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2017;52(4):259-262
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the occurrence of occult carcinoma in contralateral lobes based on the ultrasonic features of unilateral papillary thyroid carcinoma.
Methods:The study included 202 consecutives cases of unilateral papillary thyroid carcinoma with benign nodules in the contralateral lobe identified by preoperative ultrasound or fine-needle aspiration from June 2014 to December 2015. All patients received total thyroidectomies, and with postoperative pathological examination they were divided into two groups, one including 60 cases with positive occult cancer and another one consisting of 142 cases with negative occult cancer. Univariate and multivariate analyses were performed to analyze the sonographic features of unilateral papillary thyroid carcinoma relevant to the occurrence of occult carcinoma in the contralateral nodules.
Results:Univariate analysis indicated occult carcinoma in the contralateral lobes was associated with Hashimoto's thyroiditis(χ2=3.955, P=0.047), unclear border (χ2=4.375, P=0.036)and multifocality in the ipsilateral(χ2=7.375, P=0.007), but not with tumors maximum size, location, A/T, shape, internal structure, internal echo, acoustic halo, calcification, capsular invasion and blood flow signal in the lobe with carcinoma on another side. Multivariate analysis showed unclear border (OR=2.727, P=0.010) and multifocality in the ipsilateral(OR=2.807, P=0.005)of carcinoma were independent predictive factor for contralateral occult PTC.
Conclusions:Unclear border and multifocality of PTC in the ipsilateral were closely relevant to the occurrence of occult carcinoma in the contralateral nodules.
