Research progress of miR-155 and virus infections
10.3760/cma.j.issn.1003-9279.2017.04.023
- VernacularTitle: miR-155与病毒感染的研究进展
- Author:
Qi ZHOU
1
;
Yu JIN
Author Information
1. Children’s Hospital of Nanjing Medical University, Nanjing 210008, China
- Publication Type:Review
- Keywords:
MiR-155;
Virus infections;
Immunity
- From:
Chinese Journal of Experimental and Clinical Virology
2017;31(4):379-383
- CountryChina
- Language:Chinese
-
Abstract:
miR-155 is a typical multifunctional microRNA, and it participates in diverse biological processes mediated by its downstream genes, including inflammation, immunity, angiocardiopathy, and tumorgenesis. miR-155 plays a vital role in the process of virus infections, such as hepatitis B virus, human immunodeficiency virus, Epstein-Barr virus, enterovirus 71. Recent studies have shown that miR-155 regulates the replication of the virus and the antiviral reaction by JAKs/STATs and TLRs/NF-κB pathway.
