Research advances in nonalcoholic fatty liver disease and alcoholic liver disease in 2016
10.3760/cma.j.issn.1007-3418.2017.03.005
- VernacularTitle: 非酒精性脂肪性肝病与酒精性肝病2016年研究进展
- Author:
Yushuai CHEN
1
;
Bingyuan WANG
1
;
Youming LI
2
Author Information
1. Department of Elderly Gastroenterology, the First Affiliated Hospital, China Medical University, Shengyang 110001, China
2. Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China
- Publication Type:Journal Article
- Keywords:
Fatty liver, non-alcoholic;
Alcoholic liver disease;
Pathophysiology
- From:
Chinese Journal of Hepatology
2017;25(3):181-186
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic fatty liver disease (NAFLD) has become the most important liver disease in the world and its prevalence rate still tends to increase. However, there are still no effective drugs so far. The complex and dynamic interactions between multiple effects/mediators in the pathophysiology of NAFLD provide new insights and help with stratification and redefinition of clinical phenotypes and evaluation of disease susceptibility and multiplicity of progression. They may also provide new targets for future treatment. Therefore, research on the pathophysiology of NAFLD is imperative. Alcoholic liver disease is a great harm to health and an important cause of end-stage liver disease. Some progress has been made in the research on alcoholic liver disease around the world in 2016. This article reviews the research advances in alcoholic liver disease in 2016 from the aspects of epidemiology, pathogenesis, diagnostic and therapeutic methods, and prognosis.