Analysis of hepatitis B infection and immune status of the first-year students in a university
10.3760/cma.j.issn.1003-9279.2017.03.012
- VernacularTitle: 山东某高校大学新生乙型肝炎病毒感染及免疫分析
- Author:
Wenhua GAO
1
;
Xiang SU
2
;
Yi YANG
3
;
Zeming QIN
4
;
Xin LI
4
;
Li ZHAO
4
Author Information
1. Shandong University Campus Hospital, Jinan 250100, China
2. Tengzhou Central People′s Hospital, Tengzhou 277500, China
3. The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital of Shandong University, Jinan 250012, China
4. Department of Laboratory Science of Microbiology, School of Public Health, Shandong University, Jinan 250012, China
- Publication Type:Journal Article
- Keywords:
University students;
Hepatitis B vaccine;
Inoculation rate;
HBsAg;
Anti-HBs
- From:
Chinese Journal of Experimental and Clinical Virology
2017;31(3):237-239
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the hepatitis B infection and immune status of the first-year students in a university and to provide evidence for the hepatitis B prevention in the university.
Methods:Subjects were the first-year students in a university; questionnaires were distributed. Enzyme-linked immunosorbent assay (ELISA) was adopted to test HBsAg and anti-HBs in serum.
Results:The hepatitis B vaccine inoculation rate was 80.8% among 728 subjects, the inoculation rate of urban students was higher than that of rural students (P<0.005). The HBsAg positive rate was 3.4%, no significant difference was found among students in cities and countryside. The anti-HBs positive rate was 65.2%, the positive rate of urban students was higher than that of rural students (P<0.005). The positive rate of anti-HBs in students with hepatitis B vaccination history was significantly higher than that of students without history of vaccination against hepatitis B. No significant differences were found between male and female students for all the groups.
Conclusions:By combining the condition of inoculation history of the first-year students in the university and the testresult of HBsAg and anti-HBs, it is necessary to strengthen vaccination against hepatitis B. The prevention of hepatitis B and inoculation of hepatitis B vaccine in the countryside should be strengthened.
