Parallel test of anti-HCV and HCV-RNA can enhance the ability to detect HCV infection
10.3760/cma.j.issn.1003-9279.2017.02.010
- VernacularTitle: 并联检测抗-HCV和HCV-RNA可提高HCV感染检出率
- Author:
Naizhe LI
1
;
Yenjiao YIN
1
;
Wenting ZHOU
1
;
Changhong HUANG
2
;
Feng WANG
1
;
Zhiyuan JIA
1
;
Yong ZHANG
1
;
Shengli BI
1
Author Information
1. Key Laboratory for Medical Virology, Minstry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
2. Kaifeng Center for Disease Control and Prevention, Kaifeng 475000, China
- Publication Type:Journal Article
- Keywords:
Hepatitis C;
Polymerase chain reaction;
Screening
- From:
Chinese Journal of Experimental and Clinical Virology
2017;31(2):131-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the method of enhancing the ability to detect HCV infection and to provide the advice for practical work.
Methods:A total of 487 samples from a village in Hebei Province were selected by cluster sampling. Serum samples were detected by anti-HCV and HCV-RNA assays. The results were compared between the two tests. The correlation of HCV-RNA quantification and its anti-HCV s/n value was analyzed.
Results:The positive values of anti-HCV and HCV-RNA were 22.1% and 14.2%, respectively, which were lower than that of the parallel test (χ2=4.0000, P=0.0455, χ2=42.0000, P <0.0001). The HCV-RNA quantification of the samples was positively correlated with the anti-HCV s/n value, which means anti-HCV s/n value increased with HCV-RNA quantification.
Conclusion:The parallel test of anti-HCV and HCV-RNA can enhance the ability to detect HCV infection.
