Chemical constituents of Uvaria grandiflora
10.11665/j.issn.1000-5048.20190605
- VernacularTitle:大花紫玉盘的化学成分
- Author:
Qian ZHU
1
;
Qilong HUANG
;
Chunlei ZHANG
;
Zhengyu CAO
Author Information
1. 中国药科大学江苏省中药评价与转化重点实验室
- Publication Type:Journal Article
- Keywords:
Uvaria grandiflora;
chemical constituents;
lignanoids;
flavanols;
isolation;
identification
- From:
Journal of China Pharmaceutical University
2019;50(6):666-671
- CountryChina
- Language:Chinese
-
Abstract:
Chemical investigation of the roots of Uvaria grandiflora by repeated column chromatography(CC)over silica gel, ODS, Sephadex LH-20, and HPLC resulted in the isolation of twelve compounds. Their structures were identified as: epicatechin-(4β→1′, 2→O→2′)-phloroglucinol(1), proanthocyanidin A-1(2), proanthocyanidin A-2(3), epicatechin(4), phlorizin(5), eriodictyol(6), erythro-guaiacylglycerol-8-O-4′-(coniferyl alcohol)ether(7), threo-guaiacylglycerol-8-O-4′-(coniferyl alcohol)ether(8), erythro-guaiacylglycerol-8-O-4′-(sinapyl alcohol)ether(9), threo-syringylglycerol-8-O-4′-(sinapyl alcohol)ether(10), burselignan(11)and icariol A2(12). Compounds 1 to 12 were all isolated from this plant for the first time, and compound 1 was a new natural product.
