Correlation between blood routine indicators and CD4+ T cell count in AIDS patients without antiviral therapy
10.3760/cma.j.issn.1008-6706.2018.17.017
- VernacularTitle: 未进行抗病毒治疗的艾滋病患者血常规指标与CD4＋T细胞计数的相关性研究
- Author:
Lijian XUE
1
;
Wenming WANG
;
Quan CHEN
;
Qingwan YAO
;
Qinfang TANG
Author Information
1. Kunshan Center for Disease Prevention and Control, Kunshan, Jiangsu 215300, China
- Publication Type:Journal Article
- Keywords:
Acquired immunodeficiency syndrome;
CD4 Lymphocyte;
Lymphocyte count;
Late diagnosis;
Correlation
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(17):2244-2248,c17-2
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between the blood routine indicators and CD4+ T, CD8+ T lymphocytes in AIDS patients without antiviral treatment, and to find a simple, cheap and effective monitoring indicator.
Methods:A study of 333 AIDS patients without antiviral treatment was performed.The methods of regression analysis and other statistical methods were applied to research the correlation between WBC, W-SCC and CD4+ T, CD8+ T cell count among HIV/AIDS.
Results:The rate of routine blood abnormalities among 333 HIV/AIDS patients was very high, the main test indicators within the reference range only accounted for 30.63%.The proportion of late diagnosis infected with HIV among women was higher than that of males.Significant correlations were observed between CD4+ Tcell count and WBC, W-SCC, W-LCC, RBC, HGB, PLT(r=0.408, 0.541, 0.157, 0.337, 0.338, 0.166). The equation between W-SCC (x) and CD4+ cell count (y) was y=120.913x+ 90.339.
Conclusion:There is a strong correlation between CD4+ T lymphocyte count and lymphocyte count in AIDS patients without antiviral treatment.It can be used as an important indicator of immune status in patients with AIDS.At the same time, we should strengthen the propaganda of AIDS prevention, promote AIDS early detection, early treatment, and improve the quality of life of AIDS patients.
